Application
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein using GluR2/3 antibody ( 82667).| Product Name | GluR2/3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GluR2/3Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GluRK2 GRIA2 GLURB GLUR2 HBGR2 GRIA2/3 GluR-K2 GluA2 GluR K2 |
|---|---|
| Target | GluR2/3 |
| Molecular Weight(MW) | 100 (note) |
| Cellular Localization | Interaction with CACNG2 promotes cell surface expression. |
Application
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein using GluR2/3 antibody ( 82667).| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
