Application
Western blot analysis of GLUR4 (pS862) expression in MCF7 Forskonlin-treated (A); mouse brain (B); mouse spleen (C); rat spleen (D) whole cell lysates.| Product Name | GluR4 (phospho Ser862) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GluR4 (phospho Ser862)Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GLUR4. The exact sequence is proprietary. |
| Modification | p-Ser862 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GRIA4 GLUR4 GLUR4C GLURD GluA4 glutamate receptor ionotropic AMPA 4 |
|---|---|
| Target | GluR4 (phospho Ser862) |
| Tissue Specificity | Recognizes endogenous levels of GluR4 (pS862) protein. |
Application
Western blot analysis of GLUR4 (pS862) expression in MCF7 Forskonlin-treated (A); mouse brain (B); mouse spleen (C); rat spleen (D) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
