Application
Human Esophagus stained with anti-GLUT-1 antibodyApplication
staining Glucose Transporter GLUT1 in human esophagous by Immunohistochemistry (FFPE-sections).| Product Name | GluT1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Glucose Transporter GLUT1Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins designated as Glut 1 to 7 facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%) all in the molecular weight range of 40 to 60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal). |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB:1:100~1:400 ICC/IF:1:20~1:100 IHC-p:1:10~1:50 |
|
| Species Reactivity | HumanRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 6513 138140 SLC2A1 GLUT1 P11166 GLUT |
|---|---|
| Target | GLUT1 |
| Cellular Localization | Integral membrane protein. Localizes primarily at the cell surface (by similarity). |
Application
Human Esophagus stained with anti-GLUT-1 antibody
Application
staining Glucose Transporter GLUT1 in human esophagous by Immunohistochemistry (FFPE-sections).| Positive Control | HepG2 cells, esophagous and breast carcinoma |
|---|---|
| Application Notes | WB:1:100~1:400 ICC/IF:1:20~1:100 IHC-p:1:10~1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide |
