Application
Immunofluorescence image of glycine-binding protein in rat brain tissue using| Product Name | Glycine Binding Protein antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Glycine Binding ProteinIonotropic glutamate receptors are oligomeric ion channel proteins, which mediate fast neurotransmission and excitatory synapses in the mammalian central nervous system. There are three distinct subfamilies, of which NMDA receptors have received particular attention because they are implicated in both synaptic plasticity and the pathogenesis of acute and chronic neurodegenerative disorders. A unique feature of the NMDA receptors is their requirement for both glutamate and the co-agonist glycine for efficient gating. Glycine increases the affinity of the receptor for the endogenous agonist glutamate. The glycine binding site is found on the NR1 subunit of the NMDA receptor. |
| Immunogen | Synthetic peptide corresponding to the glycine-binding region residues C(311) G E R N E S F T E E G L D L H(326) of rat GBP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCIPWB |
| ICC/IF: 1:500: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LOC246295 glycine- glutamate- thienylcyclohexylpiperidine-binding protein |
|---|---|
| Target | Glycine Binding Protein |
Application
Immunofluorescence image of glycine-binding protein in rat brain tissue using| Application Notes | ICC/IF: 1:500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | antisera containing 0.05% sodium azide. |
