Rabbit Polyclonal antibody to Glycoprotein VIThis gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Immunogen
GPVI antibody was raised against a 18 amino acid synthetic peptide near the center of the human GPVI.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 ug/mL
Species Reactivity
Mouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Western blot analysis of GPVI in A-20 lysate with GPVI antibody at 1ug/mL in either (A) the absence or (B) the presence of blocking peptide.
Application Notes
WB: 1 ug/mL
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.