Application
Human GNAI2 detected by Western blot in transfected HEK293 cells (left lane)| Product Name | GNAI2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to G protein alpha Inhibitor 2Gai2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gai3 and Gai1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gai2 is expressed widely in tissues and cell lines. Activation of PLC-b by Gai- coupled receptors is the result of release of Gbg subunits from Gai. Gai2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase. |
| Immunogen | Recombinant fragment - amino acids 231-351 human G protein alpha Inhibitor 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| For WB: Use at a dilution of 1:4,500 1:5,500. The use of this product can also be used for IP but it is not yet reported. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | guanine nucleotide binding protein G(i) alpha 1 subunit adenylate cyclase inhibiting G alpha protein GIP guanine nucleotide binding protein G(i) alpha1 subunit guanine nucleotide binding protein G(i) alpha guanine nucleotide binding protein (G protei |
|---|---|
| Target | GNAI2 |
Application
Human GNAI2 detected by Western blot in transfected HEK293 cells (left lane)| Application Notes | For WB: Use at a dilution of 1:4,500 1:5,500. The use of this product can also be used for IP but it is not yet reported. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide |
