Rabbit polyclonal antibody to GPRC5C (G protein-coupled receptor, family C, group 5, member C)The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPCR5C. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (93%), Rat (93%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MGC131820 antibody, RAIG-3 antibody, RAIG3 antibody, GPRC5C antibody, orphan G-protein coupled receptor antibody, retinoic acid-induced gene 3 protein antibody, retinoic acid responsive gene protein antibody, G-protein coupled receptor family C group 5 mem
Target
GPRC5C
Molecular Weight(MW)
48 kDa (note) (2)
Cellular Localization
Cell membrane; Multi-pass membrane protein , Cytoplasmic vesicle membrane; Multi-pass membrane protein
Application
Application
Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE diluted at 1:2000
Positive Control
A549 , HeLa , HepG2 , HCT116
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.