Rabbit Polyclonal antibody to GPR143This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR143. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
G protein-coupled receptor 143 , OA1 , NYS6
Target
GPR143
Tissue Specificity
Recognizes endogenous levels of GPR143 protein.
Application
Application
Western blot analysis of GPR143 expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.