Rabbit Polyclonal antibody to GPR39 (G protein-coupled receptor 39)Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human GPR39. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
G protein-coupled receptor 39 antibody
Target
GPR39
Molecular Weight(MW)
51 kDa (note)
Cellular Localization
Cell membrane; Multi-pass membrane protein
Application
Application
Whole cell extract (30 µg) was separated by 10% SDS-PAGE, and the membrane was blotted with GPR39 antibody diluted at 1:1000.
Positive Control
U87-MG
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.