Application
Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 ug/mL.Application
Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 ug/mL.| Product Name | GRB10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GRB10The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010] |
| Immunogen | GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| IF: 20 ug/mL | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Grb-10 , RSS , growth factor receptor-bound protein 10 , MEG1 , IRBP , GRB-IR |
|---|---|
| Target | GRB10 |
| Tissue Specificity | At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms. |
Application
Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 ug/mL.
Application
Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 ug/mL.| Application Notes | IF: 20 ug/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
