Rabbit Polyclonal antibody to GRB10 (growth factor receptor-bound protein 10)The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human GRB10. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, Chicken, Rhesus Monkey, BovineMouse (89%), Rat (90%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (97%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)