Application
IHC-P analysis of rat small intestine tissue using Gremlin antibody.Application
IHC-P analysis of rat brain intestine tissue using Gremlin antibody.Application
IHC-P analysis of human colon carcinoma using Gremlin antibody.Application
IHC-P analysis of rat skeletal muscle tissue using Gremlin antibody.| Product Name | Gremlin 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Gremlin 1This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml) | |
| Species Reactivity | HumanMouseChickenDogRatHorseBovine |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | gremlin 1, DAN family BMP antagonist , GREMLIN , DAND2 , PIG2 , IHG-2 , DRM , GREM1 , CKTSF1B1 |
|---|---|
| Target | Gremlin |
Application
IHC-P analysis of rat small intestine tissue using Gremlin antibody.
Application
IHC-P analysis of rat brain intestine tissue using Gremlin antibody.
Application
IHC-P analysis of human colon carcinoma using Gremlin antibody.
Application
IHC-P analysis of rat skeletal muscle tissue using Gremlin antibody.| Application Notes | P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide. |
