Rabbit polyclonal antibody to Gremlin-2This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml).
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CKTSF1B2 , DAND3 , gremlin 2, DAN family BMP antagonist , GREM2 , PRDC
Target
Gremlin-2
Application
Application
WB analysis of recombinant human Gremlin-2. Lane 1: 5 ng, Lane 2: 10 ng, Lane 3: 50 ng, Lane 4: 100 ng.
Application Notes
Western blotting (0.5-4 µg/ml).
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.