Application
Immunofluorescence of Grik5 in Human Brain cells with Grik5 antibody at 20 ug/mL.Application
Immunohistochemical staining of human brain tissue using Grik5 antibody at 2.5 ug/ml.Application
Western blot analysis of Grik5 in human brain tissue lysate with Grik5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.| Product Name | Grik5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Grik5Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik5, also known as kainate-preferring glutamate recptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (also known as KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2. In Grik2- but not Grik1-null mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface. This Grik5 antibody does not cross-react with Grik4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | excitatory amino acid receptor2 KA2 eea2 Glutamate receptor ionotropic kainate5 excitatory amino acid receptor 2 Glutamate receptor ionotropic kainate 5 Grik5 |
|---|---|
| Target | Grik5 |
| Tissue Specificity | This antibody is specific for Grik5 |
Application
Immunofluorescence of Grik5 in Human Brain cells with Grik5 antibody at 20 ug/mL.
Application
Immunohistochemical staining of human brain tissue using Grik5 antibody at 2.5 ug/ml.
Application
Western blot analysis of Grik5 in human brain tissue lysate with Grik5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85043-PEP - Grik5 Peptide Lysates: Cat. No. GTX27918 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
