Mouse monoclonal antibody [D11] to GRK1This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]
Immunogen
Full length human GRK1.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
D11
Host Species
Mouse
Tested Applications
ICC/IFIHCIHC-FIPWB
ICC/IF: 1:20 - 1:200:
Species Reactivity
HumanMouseBovine
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
GPRK1 RHOK RK G protein-coupled receptor kinase 1 GRK1
Target
GRK1
Tissue Specificity
This antibody does not cross-react with other G protein-coupled kinases.
Application
Application
Immunohistochemical analysis of Rhodopsin Kinase 1a/b in bovine retina.