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GRK2 antibody

Catalog Number:OM255527
OM255527
Discount Price
OM255527-100ul
1~2 Week
100ul
OM255527-50ul
50ul
1~2 Week
Product Profile
Product Name GRK2 antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [3F8] to GRK2The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human GRK2 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 3F8
Host Species Mouse
Tested Applications ELISAICC/IFIHC-PWB
ELISA: 1/10000.:
Species Reactivity HumanMouseMonkeyRat
Concentration 1mg/ml
Target Information
Gene Synonyms BARK1
ADRBK1
BETA-ARK1
Target GRK2
Molecular Weight(MW) 80 kDa (note)
Application

Application

Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues (left) and cervical cancer tissues (right) using GRK2 mouse mAb with DAB staining

Application

Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng)

Application

Western blot analysis using GRK2 mouse mAb against Hela (1), Jurkat (2), MOLT4 (3), RAJI (4), THP-1 (5), L1210 (6), Cos7 (7), PC-12 (8), and NIH/3T3 (9) cell lysate

Application

Immunofluorescence analysis of NIH/3T3 cells using GRK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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