Rabbit Polyclonal antibody to GRK3The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human ADRBK2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
adrenergic beta receptor kinase 2 ADRBK2 BARK2
Target
GRK3
Application
Application
Western blot analysis of extracts of various cell lines, using ADRBK2 antibody.
Application
Immunohistochemistry of paraffin-embedded human kidney cancer using ADRBK2 antibody at dilution of 1:200 (x400 lens)