Application
GSTM1 antibody detects protein by western blot analysis. A. 50 µg mouse brain lysate/extract 12% SDS-PAGE GSTM1 antibody dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Application
GSTM1 antibody detects GSTM1 protein at cytoplasm in rat heart by immunohistochemical analysis. Sample: Paraffin-embedded rat heart. GSTM1 antibody diluted at 1:400.Application
GSTM1 antibody detects GSTM1 protein by western blot analysis. A. 50 µg rat liver lysate/extract 12% SDS-PAGE GSTM1 antibody dilution: 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.Application
Human tissue extract (30 µg) was separated by 12% SDS-PAGE, and the membrane was blotted with GSTM1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Product Name | GSTM1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GSTM1 (glutathione S-transferase mu 1)Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human GSTM1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | BovineBovine (83%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | GST1 antibody GSTM1-1 antibody GSTM1a-1a antibody GSTM1b-1b antibody GTH4 antibody GTM1 antibody H-B antibody MGC26563 antibody MU antibody MU-1 antibody GSTM1 antibody HB subunit 4 antibody glutathione S-aralkyltransferase antibody glutathion |
|---|---|
| Molecular Weight(MW) | 26 kDa (note) (2) |
| Cellular Localization | Cytoplasm |
Application
GSTM1 antibody detects protein by western blot analysis. A. 50 µg mouse brain lysate/extract 12% SDS-PAGE GSTM1 antibody dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Application
GSTM1 antibody detects GSTM1 protein at cytoplasm in rat heart by immunohistochemical analysis. Sample: Paraffin-embedded rat heart. GSTM1 antibody diluted at 1:400.
Application
GSTM1 antibody detects GSTM1 protein by western blot analysis. A. 50 µg rat liver lysate/extract 12% SDS-PAGE GSTM1 antibody dilution: 1:2000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Application
Human tissue extract (30 µg) was separated by 12% SDS-PAGE, and the membrane was blotted with GSTM1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Positive Control | Human liver , Rat liver , Mouse brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
