Rabbit Polyclonal to HAP40HAP40 is a 40-kDa Huntingtin-associated protein. It is likely to contribute to the function of normal huntingtin and is a candidate for involvement in the aberrant nuclear localization of mutant huntingtin found in degenerating neurons in Huntington's disease.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
8263 F8A DXS522E HAP40 F8A1 305423 F8A2 F8A3
Target
HAP40
Tissue Specificity
Reacts with residues 314-325 [DGHGQDTSGQLP] of the 40 kDa mouse HAP40 protein. Co-immunopreciptates Huntingtin protein.
Application
Application
Western blot analysis of HAP40 in mouse brain lysate. Also can co-immunoprecipitate Huntington protein (350 kDa) [not shown on blot].
Application Notes
Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.