Application
Western blot analysis of HAT-3 expression with Jurkat cell lysate.| Product Name | HAT-3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to HAT-3Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are respectively, the enzymes devoted to thr addition and removal of acetyl groups from lysine residues on the Histone N-terminal trails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (2-6 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes 220 kDa human HAT-3. A 50 kDa unknown band can also be detected. Reactivity to other species has not been determined.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | RUNXBP2 SAS2 MYST MYST3 TIP60 MOZ Histone acetyltransferase HAT3 |
|---|---|
| Target | HAT-3 |
| Tissue Specificity | This antibody is specific for HAT-3. |
| Cellular Localization | Partially concentrated in subnuclear foci distinct from PML bodies, and excluded from the nucleoli. |
Application
Western blot analysis of HAT-3 expression with Jurkat cell lysate.| Application Notes | Western blotting (2-6 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes 220 kDa human HAT-3. A 50 kDa unknown band can also be detected. Reactivity to other species has not been determined.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal |
