IHC-P analysis of human liver tissue using HBS1L antibody at 1:100. Left to right : DAPI, HBS1L, Merge. Heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.
Rabbit Polyclonal antibody to HBS1LThis gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
Immunogen
A synthetic peptide corresponding to a C-terminal region of Human HBS1L
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
*Optimal dilutions/concentrations should be determined by the researcher.
IHC-P analysis of human liver tissue using HBS1L antibody at 1:100. Left to right : DAPI, HBS1L, Merge. Heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.