Application
Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | HDAC6 (phospho Ser22) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to HDAC6 (phospho Ser22)Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide sequence around phosphorylation site of serine 22 (P-Q-S(p)-P-P) derived from Human HDAC6. |
| Modification | p-Ser22 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | histone deacetylase 6 , HDAC6 , HD6 , JM21 |
|---|---|
| Target | HDAC6 (phospho Ser22) |
| Tissue Specificity | The antibody detects endogenous level of HDAC6 only when phosphorylated at serine 22. |
Application
Western blot analysis of extracts from NIH-3T3 tissue using HDAC6 (Phospho-Ser22) antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
