Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody. The lane on the right is treated with the antigen-specific peptide.
Rabbit Polyclonal antibody to HDAC7 (phospho Ser155)Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Peptide sequence around phosphorylation site of Serine 155(T-V-S(p)-E-P) derived from Human HDAC7A.
Modification
p-Ser155
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
histone deacetylase 7 , HDAC7A , HDAC7 , HD7A
Target
HDAC7 (phospho Ser155)
Tissue Specificity
The antibody detects endogenous levels of HDAC7A only when phosphorylated at serine 155.
Application
Application
Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody. The lane on the right is treated with the antigen-specific peptide.
Application Notes
WB: 1:500 - 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at -20˚C/1 year
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.