| Product Name | Heparanase 1 antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Heparanase 1 (heparanase)Heparan sulfate proteoglycans (HSPGs) are major components of the basement membrane and extracellular matrix. Heparanases, like HSPE, are endoglycosidases that cleave the heparan sulfate side chain of HSPGs to permit the remodeling of the extracellular matrix for cell movement or the release of bioactive molecules from the extracellular matrix or cell surface (summary by McKenzie et al., 2000 [PubMed 11027606]).[supplied by OMIM] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Heparanase 1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | HumanHuman (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HPA antibody HPA1 antibody HPR1 antibody HPSE1 antibody HSE1 antibody HPSE antibody endo-glucoronidase antibody heparanase-1 antibody heparanase antibody |
|---|---|
| Target | Heparanase 1 |
| Molecular Weight(MW) | 61 kDa (note) |
| Cellular Localization | Lysosome membrane; Peripheral membrane protein , Secreted |
| Positive Control | Synthetic peptide: 1:8,000 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
