| Product Name | Hepatitis B Virus surface antigen antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Hepatitis B Virus Surface AntigenHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein-protein interaction. |
| Immunogen | Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA: Use at an assay dependent dilution. May be used in place of whole antiserum in almost any appropriate antibody based technique. Also suitable for conjugation purposes. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Hepatitis B virus |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Target | Hepatitis B surface antigen |
|---|---|
| Tissue Specificity | reacts only with Hepatitis B surface antigen. Non-reactive with normal human serum. |
| Application Notes | ELISA: Use at an assay dependent dilution. May be used in place of whole antiserum in almost any appropriate antibody based technique. Also suitable for conjugation purposes. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide. Constituents: 0.01M PBS. pH 7.2 |
