Application
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HIRA (Ab-555) Antibody. The picture on the right is treated with the synthesized peptide.| Product Name | HIRA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to HIRACooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HIRA. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-P |
| ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TUPLE1 HIRA TUP1 like enhancer of split protein1 DGCR1 TUP1 like enhancer of split protein 1 |
|---|---|
| Target | HIRA |
| Molecular Weight(MW) | 111 kDa (note) |
| Tissue Specificity | HIRA (Ab-555) Antibody detects endogenous levels of total HIRA protein. |
| Cellular Localization | Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence. |
Application
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HIRA (Ab-555) Antibody. The picture on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
