Rabbit Polyclonal antibody to HISPPD1 (inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2)Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human HISPPD1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Xenopus laevis, BovineMouse (99%), Rat (97%), Xenopus laevis (94%), Bovine (99%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ21506 antibody FLJ23463 antibody HISPPD1 antibody IP7K2 antibody KIAA0433 antibody VIP2 antibody PPIP5K2 antibody insP6 and PP-IP5 kinase 2 antibody hsVIP2 antibody inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 anti
Molecular Weight(MW)
140 kDa (note) (11)
Cellular Localization
Cytoplasm , cytosol
Application
Application
Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using HISPPD1 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE diluted at 1:3000
Positive Control
Raji , K562
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.