Rabbit Polyclonal antibody to HIST1H1THistones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to an Internal region of Human HIST1H1T
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Dog: 92%; Human: 100%; Pig: 86%; Rabbit: 93%
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
H1T H1FT HIST1H1T DJ221C16.2
Target
HIST1H1T
Molecular Weight(MW)
22 KDa (note)
Application
Application
WB analysis of human fetal heart tissue using HIST1H1T antibody at 0.2-1μg/ml.
Positive Control
human fetal heart
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.