Rabbit polyclonal to Histone H1.2Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq]
Immunogen
KLH conjugated synthetic peptide between 111~140 amino acids from the Center region of human HIST1H1C.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
ELISA: Use at 1:1,000:
Species Reactivity
Human
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HIST1H1C H1F2 HIST1H1C Histone H1d Histone H1.2
Target
HIST1H1C
Molecular Weight(MW)
21.365 kDa (note)
Application
Application
Western blot analysis of HIST1H1C Antibody (Center) in Hela cell line lysates (35ug/lane). HIST1H1C (arrow) was detected using the purified Pab.
Application Notes
ELISA: Use at 1:1,000:
Additional Information
Form
Liquid
Storage Instructions
Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.