Application
Antibody used in CHIP on HCT116 Cells.Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Product Name | HIST1H1C Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HIST1H1C, H1.2, H1F2, MGC3992, H1C, H1s-1 |
| Product description | Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Kim, K., (2008) J. Biol. Chem. 283 (14), 9113-9126. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIST1H1C. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| HIST1H1C antibody can be used for detection of HIST1H1C by ELISA at 1:312500. HIST1H1C antibody can be used for detection of HIST1H1C by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HIST1H1C |
|---|---|
| Alternative Names | HIST1H1C H1.2 H1F2 MGC3992 H1C H1s-1 |
| Molecular Weight(MW) | 21 kDa |
Application
Antibody used in CHIP on HCT116 Cells.
Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | HIST1H1C antibody can be used for detection of HIST1H1C by ELISA at 1:312500. HIST1H1C antibody can be used for detection of HIST1H1C by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HIST1H1C antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
