Application
WB analysis of extracts from various cell lines using HLA-DPB1 antibody.Application
IHC-P analysis of human brain cancer using HLA-DPB1 antibody at a dilution of 1:200.Application
IHC-P analysis of rat spleen tissue using HLA-DPB1 antibody at a dilution of 1:200.| Product Name | HLA-DPB1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to HLA-DPB1HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human HLA-DPB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:200. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HLA-DP HLA-DP1B HLA-DPB DPB1 major histocompatibility complex class II DP beta 1 |
|---|---|
| Target | HLA-DPB1 |
| Molecular Weight(MW) | 29 kDa (note) |
Application
WB analysis of extracts from various cell lines using HLA-DPB1 antibody.
Application
IHC-P analysis of human brain cancer using HLA-DPB1 antibody at a dilution of 1:200.
Application
IHC-P analysis of rat spleen tissue using HLA-DPB1 antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:200. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
