Application
HMGCS2 antibody detects HMGCS2 protein at mitochondria on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human liver carcinoma. HMGCS2 antibody diluted at 1:500.Application
HMGCS2 antibody detects HMGCS2 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract B. 30 whole cell lysate/extract of human HMGCS2-transfected 293T cells 7.5 % SDS-PAGE HMGCS2 antibody dilution: 1:5000| Product Name | HMGCS2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial))Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 2.3.3.10) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]). Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HMGCS2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, BovineMouse (85%), Rat (85%), Bovine (82%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HMGCS2 antibody HMG-CoA synthase antibody 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) antibody hydroxymethylglutaryl-CoA synthase mitochondrial antibody 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa (note) (2) |
| Cellular Localization | Mitochondrion |
Application
HMGCS2 antibody detects HMGCS2 protein at mitochondria on human liver carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human liver carcinoma. HMGCS2 antibody diluted at 1:500.
Application
HMGCS2 antibody detects HMGCS2 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract B. 30 whole cell lysate/extract of human HMGCS2-transfected 293T cells 7.5 % SDS-PAGE HMGCS2 antibody dilution: 1:5000| Positive Control | human HMGCS2-transfected 293T cells |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
