Rabbit polyclonal antibody to HMGN3Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB : 1:1000
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
high mobility group nucleosomal binding domain 3 PNAS-24 TRIP7 PNAS-25
Target
HMGN3
Application
Application
WB analysis of MDA-MB453 cell lysate (35ug) using HMGN3 antibody.
Application
WB analysis of 293 cells either nontransfected (lane 1) or transiently transfected (lane 2) with the HMGN3 gene.
Application Notes
WB : 1:1000
Additional Information
Form
Liquid
Storage Instructions
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.