| Product Name | hnRNP A2B1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [DP3B3] to hnRNP A2B1This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. |
| Immunogen | Bacterially expressed His-hnRNP-A2 fusion protein (Human) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | DP3B3 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHCIPWB |
| 1:500 for western blot: |
|
| Species Reactivity | HumanMouseChicken |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein A |
| Gene Synonyms | DKFZp779B0244 FLJ22720 HNRNPA2 HNRNPB1 HNRPA2 HNRPA2B1 HNRPB1 RNPA2 SNRPB1 |
|---|---|
| Target | hnRNP A2B1 |
| Tissue Specificity | Human (& chicken) hnRNP A2B1. Cross reacts with mouse for IHC on lung tissue. Reacts predominantly with a 36 kDa band (A2), & a 38kDa band (B1) |
| Cellular Localization | Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues. Not found in the nucleolus. |
| Application Notes | 1:500 for western blot: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS + 0.1% sodium azide |
Data sheet for OM257276