Application
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HNRPDL Antibody. The picture on the right is treated with the synthesized peptide.| Product Name | HNRPDL antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to HNRPDLActs as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HNRPDL. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-P |
| ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Heterogeneous nuclear ri hnRPDlike protein AUrich element RNAbinding factor hnRPD-like protein hnHNRP-DL JKT41-binding protein AU-rich element RNA-binding factor JKT41binding protein hnHNRPDL Heterogeneous nuclear ribonucleoprotein Dlike HNRPDL |
|---|---|
| Target | HNRPDL |
| Molecular Weight(MW) | 46 kDa (note) |
| Tissue Specificity | HNRPDL Antibody detects endogenous levels of total HNRPDL protein. |
| Cellular Localization | Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner. |
Application
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HNRPDL Antibody. The picture on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:1000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
