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H-Ras antibody

Catalog Number:OM257449
OM257449
Discount Price
OM257449-100ul
1~2 Week
100ul
OM257449-50ul
50ul
OM257449-20ul
20ul
1~2 Week
Product Profile
Product Name H-Ras antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to H-RasThis gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human HRAS
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms HAMSV
RASH1
CTLO
C-HA RAS1
C-H RAS
K RAS
N RAS
H RASIDX
HRAS
HRAS1
Harvey rat sarcoma viral oncogene homolog
C BAS/HAS
Target H-Ras
Application

Application

Western blot analysis of extracts of various cells, using HRas antibody.

Application

Immunohistochemistry of paraffin-embedded human gastric using HRas antibody at dilution of 1:100 (40x lens).

Application

Immunohistochemistry of paraffin-embedded human gastric cancer using HRas antibody at dilution of 1:100 (40x lens).
Application Notes WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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