Rabbit polyclonal to Human HRH1The H1 Histamine Receptor has been implicated in the inflammatory cascade and allergic response. It is expressed by some inflammatory cells and by vascular smooth muscle as well as smooth muscle of other organs. Activation of this receptor expressed in the central nervous system has been shown to regulate the release of neurotransmitters and hormones. H1 receptors modulate a variety of physiological functions including arousal, anxiety, nociception, learning, and food and water intake. The histamine H1 receptor has been reported to be expressed in brain, kidney, lung, nasal cavity, placenta, skeletal and smooth muscle, synovium, and vessel. ESTs have been isolated from B-cell/lung/testis, brain, heart, liver/spleen, lung, and nerve libraries.
Immunogen
Synthetic peptide - KLH conjugated
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)