| Product Name | Hrk antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to HrkActivator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL. [provided by RefSeq] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blot analysis (1 µg/ml). However, the optimal conditions should be determined individually. The immunoaffinity purified antibody detects human Hrk fused with green fluorescent protein in crude extracts of E. coli transfected with Hrk-GFP.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BID3 |
|---|---|
| Target | Hrk |
| Tissue Specificity | This antibody is specific for Hrk. |
| Application Notes | Western blot analysis (1 µg/ml). However, the optimal conditions should be determined individually. The immunoaffinity purified antibody detects human Hrk fused with green fluorescent protein in crude extracts of E. coli transfected with Hrk-GFP.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 50% glycerol, 1% BSA, 0.02% sodium azide |
