Mouse monoclonal antibody [LK1] to HSP60This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
Immunogen
Recombinant human Heat shock protein 60
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
LK1
Host Species
Mouse
Tested Applications
IHC-FIHC-PIPIB
IHC-F:1:10~1:20 IHC-P:1:10~1:50 IP:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Clone LK1 recognises human heat shock protein 60 (Hsp60). The clone does not react with Hsp60 of bacterial origin. The epitope recognised by this clone is located between amino acids 383 and 447 of human Hsp60.
Application Notes
IHC-F:1:10~1:20 IHC-P:1:10~1:50 IP:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.