Application
Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE diluted at 1:1000| Product Name | HYAL2 antibody , Internal |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to HYAL2 (hyaluronoglucosaminidase 2)This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HYAL2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Pig, Sheep, Rhesus Monkey, BovineMouse (88%), Rat (87%), Pig (93%), Sheep (91%), Rhesus Monkey (100%), Bovine (91%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | LUCA2 antibody HYAL2 antibody hyaluronidase 2 antibody lung carcinoma protein 2 antibody PH-20 homolog antibody PH20 homolog antibody hyaluronidase-2 antibody hyaluronoglucosaminidase-2 antibody hyal-2 antibody lysosomal hyaluronidase antibody hy |
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| Molecular Weight(MW) | 54 kDa (note) (3) |
| Cellular Localization | Cell membrane; Lipid-anchor , GPI-anchor |
Application
Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 , Jurkat , Raji |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
