Rabbit Polyclonal antibody to ICAM-1ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Immunogen
Peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
BB2 CD54 P3.58 ICAM1 intercellular adhesion molecule 1 intercellular adhesion molecule 1 (CD54) human rhinovirus receptor major group rhinovirus receptor cell surface glycoprotein P3.58 human rhinovirus receptor ICAM-1
Target
ICAM-1
Molecular Weight(MW)
92 (note)
Application
Application
Western blot analysis of extracts from MDA cells using ICAM-1 Antibody .
Application
Western blot analysis of extracts from MDA cells using ICAM-1(Ab-512) Antibody
Application Notes
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.