Mouse monoclonal antibody [CBRIC2/2] to ICAM2The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Transfected COS cells expressing ICAM2 cDNA
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
CBRIC2/2
Host Species
Mouse
Tested Applications
FACS,IHC-F,IP
Flow Cytometry: Max Dilution 1/100 Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CD102
Target
CD102
Tissue Specificity
This antibody recognizes human ICAM2. Clone CBRIC2/2 is reported to inhibit interactions between ICAM2 and LFA-1 (De Fougerolles et al. 1991).
Application
Application
FACS Image Staining of human peripheral blood lymphocytes with Mouse anti-Human CD102
Application Notes
Flow Cytometry: Max Dilution 1/100 Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.