Rabbit Polyclonal antibody to ICAM5The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ICAM-5. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Species Reactivity
Human,Mouse,Rat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
intercellular adhesion molecule 5 , TLCN , TLN
Target
ICAM5
Tissue Specificity
Recognizes endogenous levels of ICAM-5 protein.
Application
Application
Western blot analysis of ICAM-5 expression in HeLa (A); HEK293T (B); Raw264.7 (C); PC12 (D) whole cell lysates.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.