Application
Western blot analysis of IDH2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.| Product Name | IDH2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IDH2Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IDH2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Human,Mouse,Monkey,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | isocitrate dehydrogenase 2 (NADP+), mitochondrial , IDP , IDPM , ICD M , IDHM , IDH , D2HGA2 , mNADP IDH |
|---|---|
| Target | IDH2 |
| Tissue Specificity | Recognizes endogenous levels of IDH2 protein. |
Application
Western blot analysis of IDH2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
