Rabbit Polyclonal antibody to IDSIduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2009]
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human IDS.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P,WB
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
iduronate 2-sulfatase, MPS2, SIDS
Target
IDS
Application
Application
IHC-P of human placenta tissue
Application
Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: A549 Cell Lysate Lane 4: MCF-7 Cell Lysate Lane 5: COLO Cell Lysate
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC. Avoid multiple freeze-thaw cycles.