Rabbit polyclonal antibody to IFITM1IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-g-induced antiproliferation and plays a role in the control of cell growth (2). IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Immunogen
The immunogen corresponding to a region within the last 50 amino acids of Human IFITM1 (Uniprot ID: P13164)
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISA,WB
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
LEU13, 9-27, Interferon induced transmembrane protein1, Interferoninduced protein 17, IFITM1, IFI17, Interferon induced transmembrane protein 1, Interferoninduced protein17, CD225, 927, Interferon-induced protein 17, Interferon induced protein 17
Target
IFITM1
Tissue Specificity
This antibody is specific for IFITM1 C-Terminus
Application
Application
Western blot analysis of IFITM1 in Jurkat cell lysate with IFITM1 antibody at (A) 2.5 and (B) 5 ug/ml.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.