Western blot analysis of IGF1R phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Rabbit Polyclonal antibody to IGF1R (phospho Tyr1161)This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
Immunogen
A synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1161
Modification
p-Tyr1161
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIPWB
WB 1:500-1:2000, IHC 1:50-1:200, IP
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Western blot analysis of IGF1R phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Application Notes
WB 1:500-1:2000, IHC 1:50-1:200, IP
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.