Application
IHC-P analysis of human breast carcinoma tissue using IGF1R (phospho Tyr1161) antibody (left). Additional staining using antigen pre-incubated IGF1R (phospho Tyr1161) antibody was also performed (right).Application
WB analysis using IGF1R (phospho Tyr1161) antibody (right). The detection using antigen pre-incubated IGF1R (phospho Tyr1161) antibody (left) was also performed.| Product Name | IGF1R (phospho Tyr1161) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to IGF-1R (phospho Y1161)This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq] |
| Modification | p-Tyr1161 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| Recommended Starting Dilutions: For WB: 1:500-1:1000. For IHC-P: 1:50-1:100. Using pH 6.0 citrate buffer solution as a antigen retrieval buffer. For ICC/IF: 1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | insulinlike growth factor1 receptor, MGC142170, MGC142172, insulin-like growth factor 1 receptor, IGFIR, IGFR, MGC18216, IGF1R, JTK13, insulinlike growth factor 1 receptor, CD221, IGF-I receptor, insulin-like growth factor I receptor, soluble IGF1R variant |
|---|---|
| Target | IGF-1R (phospho Y1161) |
Application
IHC-P analysis of human breast carcinoma tissue using IGF1R (phospho Tyr1161) antibody (left). Additional staining using antigen pre-incubated IGF1R (phospho Tyr1161) antibody was also performed (right).
Application
WB analysis using IGF1R (phospho Tyr1161) antibody (right). The detection using antigen pre-incubated IGF1R (phospho Tyr1161) antibody (left) was also performed.| Application Notes | Recommended Starting Dilutions: For WB: 1:500-1:1000. For IHC-P: 1:50-1:100. Using pH 6.0 citrate buffer solution as a antigen retrieval buffer. For ICC/IF: 1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS (without Mg2+and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide and 50% glycerol. |
