Application
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.| Product Name | IGF1R (phospho Tyr1165/Tyr1166) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to IGF1R (phospho Tyr1165/Tyr1166)This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human IGF1 Receptor. The exact sequence is proprietary. |
| Modification | p-Tyr1165/Tyr1166 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IGFR , insulin-like growth factor 1 receptor , JTK13 , IGF1R , IGFIR , CD221 |
|---|---|
| Target | IGF1 Receptor (phospho Tyr1165/Tyr1166) |
| Tissue Specificity | Recognizes endogenous levels of IGF1 Receptor (pY1165/Y1166) protein. |
Application
Western blot analysis of IGF1 Receptor (pY1165/Y1166) expression in HEK293T (A); MCF7 (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
