Western blot analysis of extracts from Mouse brain tissue using IkappaB- beta (Phospho-Thr19) Antibody. The lane on the left is treated with the antigen-specific peptide.
Rabbit Polyclonal antibody to IKB beta (phospho Thr19)The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
Immunogen
Peptide sequence around phosphorylation site of Threonine 19 (C-D-S(p)-G-L) derived from Human IkappaB- beta.
Modification
p-Thr19
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor beta IKBB NFKBIB TRIP9
Target
IKB beta (phospho Thr19)
Tissue Specificity
The antibody detects endogenous level of I kappaB- beta only when phosphorylated at Threonine 19.
Application
Application
Western blot analysis of extracts from Mouse brain tissue using IkappaB- beta (Phospho-Thr19) Antibody. The lane on the left is treated with the antigen-specific peptide.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20˚C/1 year
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.